CJC-1295 NO DAC (Mod GRF 1-29)

Modified GRF 1-29 (also known as CJC-1295 without DAC) is a Growth Hormone Releasing Hormone (GHRH). It is categorized as a growth hormone secretagogue, a compound which stimulates increased secretion of growth hormone from the pituitary gland.

Although similar to Sermorelin, Mod-GRF has four amino acid substitutions made to its chemical structure, hence the alternate name “tetrasubstituted” GRF 1-29. These changes effectively increase the stability of Mod GRF during storage, transportation, and administration while enhancing its affinity for the GHRH receptor.




Mod GRF 1-29 stimulates increased natural growth hormone production. This promotes greater muscle and lean body mass, decreased body fat, and enhanced recovery from injuries and training sessions.

The advantage of using CJC-1295 DAC instead of actual HGH injections is that injecting HGH shuts down the body’s own natural production and therefore when injections are ceased, the body’s ability to produce its own Growth Hormone may be impaired and take some time to recover. Since CJC-1295 DAC only stimulates the body’s own GH production, this risk is not apparent.

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How it works?

Like the body’s natural GHRH, Mod-GRF works by binding to the growth hormone releasing hormone receptor (or GHRHr) in the anterior part of the pituitary gland. There, it works to amplify the pulsatile release of GH, consequently provoking increases in production of IGF-1 as well. Mod GRF works most effectively when administered at the same time as a release of GH in the body. This can be accomplished by timing administration with the body’s natural GH release or by administering it along with a GHRP to further amplify both peptides’ effects.

Side Effects

Side effects of Mod GRF are typically mild and dose-dependent, with negative effects rarely occurring at moderate dosage levels. Generally, mild flushing, nausea, stomach upset, dizziness, and/or headache may occur upon initial administration. These reactions tend to dissipate after repeated injections. Feelings of tiredness or lethargy are possible as well, as growth hormone can increase the desire for sleep as well as its quality and restorative capabilities.

Excessive dosages of Mod GRF 1-29 may also lead to tingling or numbness in the hands and feet. Water retention can be another sign that the dosage is too high and should be reduced. As always, it is recommended to discontinue use and call a physician immediately if any negative side effects are suspected.

More information

CJC-1295 DAC and CJC-1295 (also known as Modified GRF 1-29) are both Growth Hormone Releasing Hormones (GHRH). Their action in the human body is identical but the difference between the two peptides are the span of the half-life. Modified GRF 1-29 and Sermorelin have a very short-acting half-life of about 30 minutes, while CJC-1295 DAC has a half-life that can last up to approximately 8 days. Many a scientist have reported that the short half-life of Sermorelin and Modified GRF 1-29 is considered to be much more natural as they produce a short pulse of Human Growth Hormone.


Mod GRF is generally administered 1-3 times daily at dosages of 100mcg per administration. For anti-ageing purposes, 100mcg can be administered once daily before bed. This protocol can provide a significant increase in growth hormone production over time while still mirroring natural patterns of GH release. For strength gain or performance enhancement, 100mcg can be administered 3 times a day in combination with a GHRP (as mentioned above). The higher dosage of Mod GRF in conjunction with the use of a GHRP can provide a substantial increase in growth hormone output. This will facilitate muscle growth, fat loss, and recovery from training and injury.
Importantly, dosages should always be monitored and adjusted by the prescribing physician based on individual results. It is a good practice to start with a more conservative dose at first, increasing only as needed to attain desired results. This helps to avoid excessive doses that can lead to unwanted side effects.


Mod GRF 1-29 stimulates increased natural growth hormone production. This promotes greater muscle and lean body mass, decreased body fat, and enhanced recovery from injuries and training sessions. In addition, it promotes deeper, more restful sleep, enhanced flexibility and joint health, and improved overall health and wellness. Growth hormone is a crucial component in numerous physiological processes, with substantial influence in the facilitation of strength, energy, flexibility, vitality, and overall well-being.

Indeed, the aging-related decline in growth hormone production is responsible for many of the debilitating effects commonly associated with getting older.

User reviews

Review 1
I’ve always found this product to be particularly effective and really high quality. Recommended!

Review 2
I’ll highly recommend Mod GRF 1-29.

Review 3

This product do deliver what it promises. Seems promising!!


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