MK-677 is one of the most popular compounds on the market right now. It’s more known for its online notoriety than its clinical research data.

You might also know MK677 as Ibutamoren or Nutrabol. As we mentioned, there’s a lot of information available out there on this compound.




MK 677 is undoubtedly one of the best ways to gain muscle mass with so many additional benefits. It is amazing how it increases the levels of growth hormone and Insulin like growth factor but does in no way effects the levels of hormones like thyroxine, cortisol or testosterone.N

Most of it shows that MK-677 is great at boosting IGF-1 and growth hormone levels. There are also plenty of other benefits associated with Ibutamoren Mesylate which we’ll explore in-depth throughout this review.

Editor’s Note: You can buy “mk-677” from our top recommended source.

How it works?

As mentioned, MK-677 works by imitating the activity of ghrelin. In case you’re wondering, ghrelin is a naturally occurring hormone.
It functions as a neuropeptide in the central nervous system. Mostly, this hormone is known for its ability to stimulate a ravenous appetite!

This is in addition to the regulation of energy distribution in the body. It also affects the way our bodies metabolize fat. It can also influence our ability to recover from conditions such as Type 2 diabetes and obesity.

When taken on its own, MK677 has the potential to boost HGH production without disturbing other hormones. Users also like the fact that Ibutamoren doesn’t suppress the body’s existing levels of growth hormones and testosterone, which is a huge bonus considering the benefits.

Side Effects

The most common side effects associated with MK677 include muscle pain and an increased appetite.

Some studies showed that participants had reduced insulin sensitivity and higher fasting blood glucose. These are the same results shown in people that have higher growth hormone levels.

Suffice to say, Ibutamoren typically exhibits mild to no side effects all save for one particular episode that stands out. In the study we mentioned above which featured elderly patients with hip fractures, MK-677 led to spikes in blood glucose, blood pressure and even a risk of congestive heart failure. As a result, the study had to be stopped because the patients that were experiencing these problems already had a history of heart failure.

That’s why it’s always a good idea to curtail carb intake and keep your insulin and blood sugar levels in check as much as you can. Taking MK-677 might help.

Of course, MK-677 is not recommended for cancer patients because it’s an anabolic substance that promotes GH and IGF-1 production.

It’s also ill-advised to take MK-677 if you’re Th 1 dominant for the same reasons mentioned above.

More information

Ibutamoren (INN) (developmental code names MK-677, MK-0677, L-163,191; former tentative brand name Oratrope) is a potent, long-acting, orally-active, selective, and non-peptide agonist of the ghrelin receptor and a growth hormone secretagogue, mimicking the growth hormone (GH)-stimulating action of the endogenous hormone ghrelin. It has been shown to increase the secretion of several hormones including GH and insulin-like growth factor 1 (IGF-1) and produces sustained increases in the plasma levels of these hormones without affecting cortisol levels.

Ibutamoren has been shown to sustain activation of the GH–IGF-1 axis and to increase lean body mass with no change in total fat mass or visceral fat. It is under investigation as a potential treatment for reduced levels of these hormones, such as in children or elderly adults with a growth hormone deficiency, and human studies have shown it to increase both muscle mass and bone mineral density, making it a promising potential therapy for the treatment of frailty in the elderly As of June 2017, ibutamoren is in the preclinical stage of development for growth hormone deficiency.


MK-677 is mostly available in capsule and liquid form. It’s recommended to take orally in daily dosages up to 25 mg. It’s up to you to split the dosage or take it all at once.
Although there are a lot of users who take a bigger dosage. We wouldn’t recommend you try that as higher dosages could expose you to serious adverse side effects.
It’s important that you start slow and slowly increase your dosage. So, for example, you can start off with 10mg of MK677 a day and up the dosage to 20-25mg a day.


There you have it! Hopefully, now you know enough about MK-677 to use it wisely.

There’s no doubt that this compound works great at increasing muscle size and strength, and it’ll help you burn fat and shed weight without sacrificing your diet.

Feel free to try it out but make sure to use it in the recommended doses and only source it from a reputable online vendor.

User reviews

Review 1
yes, mk677 is loved by many…just keep in mind you want to run it more long term to get the most out of it… I would go a minimum of 6 months… here is a link to get the best quality you can find

Review 2
mk677 is very versatile

Review 3

Review 4

Less pure and less effective compared to my previous purchase from ProMolekules. These guys need to up their game when it comes to purity. It was hardly effective and mostly induced hunger. Previous batch was purer and had resulted in nice gains & GH secretagogue related effects.

My recent order of RAD140 from ProMolekules was worst, the vial had soapy fizz in it. Wonder if they’re clearing out bad batches. They need to up their manufacturing & operations. The sticker that says “Made in USA” is a plain lie.


There are no reviews yet.

Be the first to review “Mk-677”

Your email address will not be published. Required fields are marked *