Norditropin

Norditropin is a polypeptide hormone of recombinant DNA origin. The hormone is synthesized by a special strain of E. coli bacteria that has been modified by the addition of a plasmid which carries the gene for human growth hormone.

Category:

Description

Introduction

Norditropincontains the identical sequence of 191 amino acids constituting the naturally occurring pituitary human growth hormone with a molecular weight of about 22,000 Daltons.

Norditropin NordiFlex is used to treat growth failure in children:
If they have no or very low production of growth hormone (growth hormone deficiency)

If they have Turner syndrome (a genetic problem which may affect growth)

If they have reduced kidney function

If they are short and were born small for gestational age (SGA).

Norditropin NordiFlex is used as a growth hormone replacement in adults:

In adults, Norditropin Nordiflex Pen 5mg is used to replace growth hormone if their growth hormone production has been decreased since childhood or has been lost in adulthood because of a tumour, treatment of a tumour, or a disease that affects the gland which produces growth hormone. If you have been treated for growth hormone deficiency during childhood, you will be retested after completion of growth. If growth hormone deficiency is confirmed, you should continue treatment.

Editor’s Note: You can buy “Norditropin” from our top recommended source.

How it works?

Norditropin Nordiflex Pen 5mg contains a biosynthetic human growth hormone called somatropin which is identical to the growth hormone produced naturally in the body. Children need growth hormones to help them grow, but adults also need it for their
general health.

Always use this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.

Side Effects

Do not use Norditropin NordiFlex If you are allergic to somatropin, to phenol, or to any of the other ingredients of this medicin-
If you have had a kidney transplant
If you have an active tumour (cancer). Tumours must be inactive and you must have finished your anti-tumour treatment before you start your treatment with Norditropin NordiFlex
If you have an acute critical illness e.g. open heart surgery, abdominal surgery, multiple accidental trauma, or acute respiratory failure
If you have stopped growing (closed epiphyses) and you do not have a growth hormone deficiency.

Warnings and precautions
Talk to you doctor or pharmacist before using Norditropin Nordiflex Pen 5mg
If you have diabetes
If you have ever had cancer or another kind of tumour
If you have recurrent headaches, eyesight problems, nausea, or if vomiting occurs
If you have abnormal thyroid function
If you develop a limp or low back pain as these could be signs of a curved spine (scoliosis)
If you are over 60 years of age or have received somatropin treatment as an adult for more than 5 years, as experience is limited
If you suffer from kidney disease as your kidney function should be monitored by your physician.
Other medicines and Norditropin NordiFlex
Tell your doctor or pharmacist if you are using, have recently used or might use any other medicines.
Glucocorticoids or sex steroids (for example anabolic steroids and estrogen) – your adult height may be affected if you use
Norditropin Nordiflex Pen 5mg and glucocorticoids or sex steroids at the same time
Cyclosporin (immunosuppressive) – as your dose may need to be adjusted
Insulin – as your dose may need to be adjusted
Thyroid hormone – as your dose may need to be adjusted
Gonadotrophin (gonad stimulating hormone) – as your dose may need to be adjusted
Anticonvulsants – as your dose may need to be adjusted.
Pregnancy and breast-feeding
Somatropin containing products are not recommended in women of childbearing potential not using contraception.
Pregnancy. Stop the treatment and tell your doctor if you become pregnant while you are using Norditropin NordiFlex
Breast-feeding. Do not use Norditropin Nordiflex Pen 5mg while you are breast-feeding because somatropin might pass into your milk.
Driving and using machines
Norditropin NordiFlex does not affect the use of any machines or the ability to drive safely.

More information

Norditropin NordiFlex is used to treat growth failure in children:
If they have no or very low production of growth hormone (growth hormone deficiency)
If they have Turner syndrome (a genetic problem which may affect growth)
If they have reduced kidney function
If they are short and were born small for gestational age (SGA).
Norditropin NordiFlex is used as a growth hormone replacement in adults:
In adults, Norditropin Nordiflex Pen 5mg is used to replace growth hormone if their growth hormone production has been
decreased since childhood or has been lost in adulthood because of a tumour, treatment of a tumour, or a disease that affects
the gland which produces growth hormone. If you have been treated for growth hormone deficiency during childhood, you will be
retested after completion of growth. If growth hormone deficiency is confirmed, you should continue treatment.

Dosages

Recommended dose
The dose for children depends on their body weight and body surface area. Later in life, the dose depends on your height, weight, gender, and growth hormone sensitivity and will be adjusted until you are on the right dose.

Children with low production or lack of growth hormone:
The usual dose is 0.025 to 0.035 mg per kg body weight per day or 0.7 to 1.0 mg per m2 body surface area per day

Children with Turner syndrome:
The usual dose is 0.045 to 0.067 mg per kg of body weight per day or 1.3 to 2.0 mg per m2 body surface area per day

Children with kidney disease:
The usual dose is 0.050 mg per kg of body weight per day or 1.4 mg per m² body surface area per day

Children born small for gestational age (SGA):
The usual dose is 0.035 mg per kg of body weight per day or 1.0 mg per m2 body surface area per day until final height is
reached. (In clinical trials of short children born SGA doses of 0.033 and 0.067 mg per kg body weight per day have typically
been used)

Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date, which is stated on the package after EXP/. The expiry date refers to the last
day of that month.
Store unused Norditropin Nordiflex Pen 5mg in a refrigerator (2°C – 8°C) in the outer carton, in order to protect from light.
Do not freeze or expose to heat.
While using Norditropin NordiFlex 5 mg/1.5 ml, you can either:
Keep it for up to 4 weeks in a refrigerator (2°C – 8°C), or
Keep it for up to 3 weeks at room temperature (below 25°C).
Do not continue to use Norditropin Nordiflex Pen 5mg if they have been frozen or exposed to excessive temperatures.
Do not use Norditropin Nordiflex Pen 5mg if the growth hormone solution is cloudy or discoloured.
Always store Norditropin NordiFlex without a needle attached.
Always keep the pen cap fully closed on the Norditropin NordiFlex when you are not using it.
Always use a new needle for each injection.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no
longer use. These measures will help protect the environment.

Conclusion

Novo Nordisk has been helping patients with growth-related hormone disorders around the world for 40 years, and Norditropin®
has been FDA-approved in the United States since 1995. Find quick facts about our history, milestones, and our commitment to
the growth hormone therapy community.

User reviews

Review1
Generally if it is not reconstituted (meaning that it is not yet mixed), then it should hold out well at room temperature for a month or two and perhaps longer. But quite honestly that is the danger with hgh,it can lose it`s potence and sometimes all potency. Big name brands will ship from manufacturing date direct to your door in dry ice. Now again, it`s not mixed yet so it should be OK. But I suggest you ask naps this question because they can reassure you or at least give you more guidance.

Review2
Anything that’s has no water in it is fine to be in transit even though it wasn’t at optimum storing temperature. Water acts as a medium for enzymes/bacteria to move around and degrade it(breakdown) the chemical bonds. This is a recombinant proteins so it was lyophilized (freeze dried) in a lab so it has no water in it. So you are good my friend! now if you order Pre-mixed with water in it (medium) then it will be an issue in transit. Then it will need to be shipped in a cold packed or dried ice. But even in solution if the condition was sterile and no enzymes is in the vial it would be fine for a while. The potency might be a little less but I would not worry because this was not the case. You are good my friend!! And good luck!

Review 3
This HGH is NOT premixed. The norditropin simplex website say the cartridge must be stored between 2 and 8 degrees Celsius prior to first use. My package of norditropin has been in Turkey since may 21st and I`m assuming its warmer then 8° Celsius. Is my norditropin cartridge going to go bad during the 2-3 weeks it takes to arrive? For $365 plus a $50 HGH shipping fee I expect to get prescription grade HGH but with the amount of time it`s in transit outside of the recommended storage temperature range I fear it going bad before it arrives. Anyone have any experience with this? Please do not use this post to recommend any grey blue green tops, I`m interested in the NORDS only. Thank you

Review 4

My son started with Norditropin in December and so far, he has grown 2 inches his doctor stated, we can expect to see 4 inches in the first year and so far, he is on schedule. he has not experienced any of the side effects that comes with using Norditropin which is wonderful. I am hopeful for a height expectancy of 5’7 right now, he is 14 and 4’11.

Reviews

There are no reviews yet.

Be the first to review “Norditropin”

Your email address will not be published.