Humatrope HGH

Humatrope (somatropin, rDNA origin, for injection) is a polypeptide hormone of recombinant DNA origin. Humatrope (somatropin rdna origin) is synthesized in a strain of Escherichia coli that has been modified by the addition of the gene for human GH. The peptide is comprised of 191 amino acid residues and has a molecular weight of about 22,125 daltons. The amino acid sequence of the peptide is identical to that of human GH of pituitary origin.

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Description

Introduction

Humatrope is a man-made form of human growth hormone. It was first approved in 1987 to treat children who are growing slowly because they do not make enough growth hormone on their own.

Growth hormone is essential for growth—made by the pituitary gland (located at the base of the brain), then released into the bloodstream, where it travels to the body’s tissues. Here it stimulates production of another hormone important for growth, called insulin-like growth factor 1, or IGF-1. Growth hormone works to stimulate growth, in large part due to its effect in producing IGF-1.

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How it works?

Humatrope is a man-made form of growth hormone. Growth hormone is essential for growth—made by the pituitary gland (located at the base of the brain), then released into the bloodstream, where it travels to the body’s tissues. Here it stimulates production of another hormone important for growth, called insulin-like growth factor 1, or IGF-1. Growth hormone works to stimulate growth, in large part due to its effect in producing IGF-1.

Side Effects

● Common side effects may include:
● pain, itching, or skin changes where the medicine was injected;
● swelling, rapid weight gain;
● muscle or joint pain;
● numbness or tingling;
● stomach pain, gas;
● headache, back pain; or.
● cold or flu symptoms, stuffy nose, sneezing, sore throat, ear pain.

Before using somatropin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as benzyl alcohol found in some brands), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

More information

Humatrope (somatropin rdna origin) is a sterile, white, lyophilized powder intended for subcutaneous or intramuscular administration after reconstitution to its liquid form. Humatrope (somatropin rdna origin) is a highly purified preparation. Phosphoric acid and/or sodium hydroxide may have been added to adjust the pH. Reconstituted solutions have a pH of approximately 7.5. This product is oxygen sensitive.

Dosages

Vial — Each vial of Humatrope (somatropin rdna origin) contains 5 mg somatropin (15 IU or 225 nanomoles); 25 mg mannitol; 5 mg glycine; and 1.13 mg dibasic sodium phosphate. Each vial is supplied in a combination package with an accompanying 5-mL vial of diluting solution (diluent). The diluent contains Water for Injection with 0.3% metacresol as a preservative and 1.7% glycerin.
Cartridge — Cartridges of Humatrope (somatropin rdna origin) contain either 6 mg (18 IU), 12 mg (36 IU), or 24 mg (72 IU) of somatropin. Each cartridge is supplied in a combination package with an accompanying syringe containing approximately 3 mL of diluting solution (diluent). The diluent contains Water for Injection; 0.3% metacresol as a preservative; and 1.7%, 0.29%, and 0.29% glycerin in the 6, 12, and 24 mg cartridges, respectively.

Conclusion

Although results may be different for everyone, Humatrope has data from clinical studies to help support treatment decisions. Throughout treatment, help your child remember that growth is a gradual process that takes time, even with treatment. Talk with your doctor about setting realistic expectations for your child’s treatment, and include your child in the conversation. Helping a child understand what to expect may help them stay motivated to continue therapy.

User reviews

Review 1
This medicine works great. My problem is the price! I qualified for the humatrope card that helps with the 28day cost. I have insurance and the cost is VERY HIGH! My part after insurance is almost $200 every 28 days. I am allowed $2400 for 24 months. I ran out of that benefit amount in October. I had to pay $200 every 28 days for the remainder of 2019. Now that it is January 2020 they said I only have 10 more months of assistance.

Review 2
Tingling, itching and numbness of my hands. Sleeplessness leading to insomnia. Higher glucose numbers no matter the diet nearing diabetes.”

Review 3
“This works quite well for me. I don’t know if anyone else uses it or had adult onset growth hormone deficiency and also developed this condition from Gulf War Syndrome. When I started taking the Humatrope, my bone density went from a -4 to a -2.3 and hopefully is still going up. My focus and concentration improved and my irritability and my energy level went way up! I have been using it for about 5 years now and didn’t know I had it until my urologist started listing reasons for severe osteoporosis and it turns out that I had adult onset growth hormone deficiency. Good luck to all. Hopefully Stem Cell technology can be used to help cure/fix us!”

Review 4

My son began taking Humatrope at the age of 5 and in almost 3 years he has grown just over 10 inches and gained around 10 lbs. When he began he was not on the growth chart at all and was not moving up as he should. After testing found him to be growth hormone deficent he began the daily shots and now is in the 25% on the growth chart! He will continue to take Humatrope until he is finished growing so we still have years of shots ahead of us but for us AND HIM they are proving to be worth it.

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